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Overdosage
Check with your doctor immediately in case you suspect an overdose. When taken by people with kidney disorders, excessive doses of Valtrex have been known to cause psychological problems and kidney fa
ilure.
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Possible food and drug interactions
If you are taking Valtrex with certain other drugs, the effect of either drug could be increased, decreased, or altered. Check with your doctor before combining Valtrex with cimetidine (Tagamet) and/o
r probenecid (Benemid).
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Special warnings about this medication
High doses of Valtrex have proved dangerous in people whose immune system is compromised because of HIV infection, bone marrow transplant, or kidney transplant.
If your kidneys are not funct
ioning properly, or you are taking drugs that may damage the kidneys such as Neomycin or Streptomycin, Valtrex can make your condition worse or affect your central nervous system (brain and spinal cor
d).
Effects on the central nervous system are more common in older adults, leading to such symptoms as agitation, confusion, and hallucinations. Their kidneys are also more likely to be affe
cted; and those with kidney problems need a smaller dose. Older adults tend to suffer the pain of shingles for a longer time after healing has begun.
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Why is this medication prescribed?
Valtrex (val-ay-SYE-kloe-veer) is used to treat the symptoms of herpes zoster (also known as shingles), a herpes virus infection of the skin; it is also used to treat and prevent genital herpes infect
ions. In your body, Valtrex becomes the anti-herpes medicine, acyclovir. Although Valtrex will not cure shingles or genital herpes, it does help relieve the pain and discomfort and helps the sores hea
l faster.
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Before Using This Medicine
Pregnancy¡XAdequate and well-controlled studies in humans have not been done with Valtrex or acyclovir. However, acyclovir has been used in pregnant women and has not been reported to cause birth defe
ts or other problems.
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Side Effects of This Medicine
Check with your doctor as soon as possible if the following side effect occurs:
- Painful menstruation, including abdominal cramps, diarrhea, or nausea
- Black, tarry stools; ches
t pain; chills; cough; decreased frequency/output of urine; fever; flu-like symptoms; headache; lower back/side pain; reduced mental alertness; shortness of breath; unusual tiredness; yello
w eyes or skin
- Back, leg or stomach pains; changes in behavior, especially in interactions with other people; difficulty breathing or swallowing; fast, pounding, or irregular heartbeat
; high blood pressure; itching; lightheadedness when getting up from a lying or sitting position; redness of skin ;
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